Macide, the daughter of a poor family who has studied psychology and is not happy in business life and seeks to heal others, falls in love with the elder brother of Ahmet, Kazım Işık, who is known as the smartest and the most successful businessman in the country. She has just met and fallen in love with the man with a morbid passion. Moreover, Kazım Işık is married to Nermin. Macide’s love is not unrequited. Kazım passionately embraces Macide, who is by his side at his weakest moment… But will he be able to protect her from the cruelty of the rich and powerful life he created? Will Macide be able to preserve the purity, innocence and sensitivity she had when she first met Kazım? Or worse yet, when everyone makes her a “queen” out of false reverence… This is the story of a young woman who falls in love for the first time on her way to heal herself by healing others, following the healing she received from her father. The story of a man who has everything he wants in life, but perhaps mostly for this reason, looking for a companion in unhappiness and loneliness… Poison Ivy is a love story that tells that when two souls find each other despite the whole world, even themselves. Everything stands in front of them but still, they meet. However, no one can illuminate another’s darkness.
   

The injustices she witnessed in her corporate business life pushed human resources specialist Macide to seek a way out. Realizing that her salvation can only be achieved by helping others, Macide decides to embark on the path of healing, which she received from her father when she was a child. On that note, she resigns from her job and leaves Ankara to go to Istanbul to receive an education. On the way, Macide meets Ahmet Işık from the pharmaceutical giant Işık Family. Ahmet falls in love with Macide at first sight. Believing that she will find healing as she heals, Macide's path crosses with the family of Işık, woven with wounds and secrets from the past, and Kazım Işık, the elder brother of Ahmet, the leader of that world.

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